Clinical practice regarding dopamine-agonist use and driving in Parkinson's disease

Can J Neurol Sci. 2007 Nov;34(4):438-42. doi: 10.1017/s0317167100007320.

Abstract

Background: Current Health Canada instructions for use of the dopamine agonists (DA), pramipexole and ropinirole, state that Parkinson's disease (PD) patients should be told not to drive. The objective was to assess neurologists' actual clinical practice concerning driving advice they give to PD patients starting a DA.

Methods: An online survey was created consisting of 4 items regarding demographics, 5 regarding PD and driving, and 9 regarding DA use and driving. The survey was distributed to 563 neurologists.

Results: In total 96 neurologists (17.9%) responded. 4.4% tell patients with PD not to drive, solely because they are taking a DA. Respondents assess the patient's tendency for excessive daytime sleepiness and sleep attacks after starting a DA more frequently than after starting other dopaminergic drugs (p < 0.001).

Discussion: A minor proportion of the clinicians responding to our survey advise PD patients not to drive, solely because they use a DA. Such being the case, we propose that current Health Canada guidelines need revision.

MeSH terms

  • Automobile Driving*
  • Canada
  • Disorders of Excessive Somnolence / chemically induced
  • Dopamine Agonists / adverse effects
  • Dopamine Agonists / therapeutic use*
  • Guideline Adherence / statistics & numerical data*
  • Guidelines as Topic
  • Humans
  • Parkinson Disease / drug therapy*
  • Practice Patterns, Physicians' / statistics & numerical data*

Substances

  • Dopamine Agonists