Picosecond infrared probing of the vibrational spectra of transients formed upon UV excitation of stacked G-tetrad structures

Chem Commun (Camb). 2007 Dec 28:(48):5158-60. doi: 10.1039/b711172j. Epub 2007 Sep 13.

Abstract

The photophysical properties of stacked G-tetrads in diverse systems, including concentrated solutions of 5'-guanosine monophosphate (5'-GMP), polyguanylic acid (poly(G)) and the G-rich oligodeoxynucleotide sequence characteristic of human telomeric DNA, are probed by ps-TRIR and compared to those of the monomeric 5'-GMP.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • DNA / chemistry
  • DNA / radiation effects
  • Guanosine Monophosphate* / chemistry
  • Guanosine Monophosphate* / radiation effects
  • Humans
  • Hydrogen Bonding
  • Molecular Structure
  • Oligodeoxyribonucleotides* / chemistry
  • Oligodeoxyribonucleotides* / radiation effects
  • Phosphates / chemistry
  • Phosphates / radiation effects
  • Poly G* / chemistry
  • Poly G* / radiation effects
  • Spectrophotometry, Infrared / methods
  • Telomere / chemistry
  • Telomere / radiation effects
  • Time Factors
  • Ultraviolet Rays*
  • Vibration

Substances

  • Oligodeoxyribonucleotides
  • Phosphates
  • Poly G
  • Guanosine Monophosphate
  • DNA