This article describes an optional mode of treatment for a partially edentulous patient with severe microstomia, severe changes to the intraoral soft tissues, and compromised hand function. The principles discussed in this article describe a patient with systemic sclerosis but are applicable to any patient who suffers from scarring in the oral and facial areas due to disease, trauma, or burning injuries. Since dental implants were contraindicated, it was determined that long-term comfort and function could be achieved only through the use of a removable partial denture (RPD). A Valplast flexible RPD was used because of its unique characteristics and a specially designed folded custom impression tray was used to obtain an accurate impression of hard and soft tissues. This article describes the complete process and management of the patient's needs, focusing on the decision-making process for the chosen treatment plan, the special impression technique, and the completion of the RPD.