Objective and non-invasive evaluation of dry mouth

Shin-ichi Ishimoto; Kouichi Tsunoda; Youko Fujimaki; Kazunari Okada; Yuuki Saito; Makoto Kinoshita; Naonobu Takeuchi

doi:10.1016/j.anl.2007.05.002

Objective and non-invasive evaluation of dry mouth

Auris Nasus Larynx. 2008 Mar;35(1):89-93. doi: 10.1016/j.anl.2007.05.002. Epub 2007 Nov 26.

Authors

Shin-ichi Ishimoto¹, Kouichi Tsunoda, Youko Fujimaki, Kazunari Okada, Yuuki Saito, Makoto Kinoshita, Naonobu Takeuchi

Affiliation

¹ Department of Otolaryngology, Social Insurance Central General Hospital, 3-22-1 Hyakuninn-cho, Shinnjyuku-ku, Tokyo 169-0073, Japan. shinchan-tky@umin.ac.jp

PMID: 18037254
DOI: 10.1016/j.anl.2007.05.002

Abstract

Objective: This study was designed to evaluate the moisture checker (MucusIII), a new device for measuring moisture of the oral submucosa.

Methods: Defective salivary secretion was induced by sialoadenectomy (n=8), while the remaining five guinea pigs underwent sham surgery (control group). We measured the unstimulated salivary flow rate, wetness of the oral mucosa using the oral tester (L-SALIVO) and moisture of the submucosa of the tongue using MucusIII. All tests were performed before (baseline) and 1 month after surgery.

Results: Sialoadenectomy significantly reduced both the salivary flow rate and the tester reading at 10 and at 30s (p<0.01). The vale due to the MucusIII as significantly reduced in animals with sialoadenectomy (p<0.01).

Conclusion: The MucusIII is a device for objective evaluation of the moisture of the oral cavity.

MeSH terms

Animals
Diagnosis, Computer-Assisted / instrumentation*
Disease Models, Animal*
Equipment Design
Guinea Pigs
Male
Mouth Mucosa / physiopathology
Salivation / physiology*
Sensitivity and Specificity
Submandibular Gland / physiopathology
Submandibular Gland / surgery
Tongue / physiopathology
Xerostomia / diagnosis*
Xerostomia / physiopathology