Abstract
Bacteria "talk" with each other by using small molecules that enable individuals in a population to coordinate their behavior. This language is termed quorum sensing. Bacterial pathogens may use this language to decide when to attack a host organism; therefore, the development of artificial signals to interfere with this signal process has become an area of intense chemical research.
Publication types
-
Research Support, Non-U.S. Gov't
-
Review
MeSH terms
-
Bacterial Physiological Phenomena* / drug effects
-
Drug Design*
-
Immunity / drug effects
-
Quorum Sensing / immunology*
-
Repressor Proteins / agonists
-
Repressor Proteins / antagonists & inhibitors
-
Trans-Activators / agonists
-
Trans-Activators / antagonists & inhibitors
Substances
-
Repressor Proteins
-
Trans-Activators
-
LuxR autoinducer binding proteins