Increased incidence of mucosal candidiasis after HAART initiation: a benign form of immune reconstitution disease?

AIDS. 2007 Nov 30;21(18):2534-6. doi: 10.1097/QAD.0b013e3282f02a3a.

Abstract

Immune reconstitution after HAART initiation is often complicated by adverse clinical manifestations caused either by the unmasking of preexisting untreated opportunistic infections or the clinical deterioration of a known and treated opportunistic infection. The present study was conducted to determine whether the initiation of HAART was followed by an increase in the incidence of mucosal candidiases, a possible manifestation of immune reconstitution disease of the unmasking type.

Publication types

  • Multicenter Study

MeSH terms

  • AIDS-Related Opportunistic Infections / etiology*
  • Antiretroviral Therapy, Highly Active / adverse effects*
  • Candidiasis / epidemiology
  • Candidiasis / etiology*
  • Female
  • French Guiana / epidemiology
  • HIV Infections / drug therapy
  • HIV-1
  • Humans
  • Immune Reconstitution Inflammatory Syndrome / epidemiology
  • Immune Reconstitution Inflammatory Syndrome / etiology*
  • Incidence
  • Male
  • Middle Aged
  • Retrospective Studies