[Endoscopic treatment with Deflux for primary vesicoureteral reflux]

Actas Urol Esp. 2007 Sep;31(8):880-4. doi: 10.1016/s0210-4806(07)73743-9.
[Article in Spanish]

Abstract

Purpose: Effectivety for endoscopic treatment for primary reflux has been under discussion as a single procedure. In the last 3 years our unit have been used Deflux, (dextranomer copolymer in hialuronic acid) for this pathology. The aim of this study is to analyze the results of our experience.

Material and methods: Since 2002, a prospective protocol for VUR has been applied. We reviewed the last 25 cases treated with Deflux per thousand injection who had ultrasound and cistography.

Results: 86% (n = 21) were females and with a mean age of 6.1 years (range 2-14) the success rate with a single injection was 73.6% (n = 28). The amount of deflux injected was irrelevant in the result. The results in the low grades reflux (I-II) reaching the 100% (n = 15). The worse result was in the double system cases with just one successful case out of 6 injected. The procedure was in outpatient bases. There were no peri-procedures complications.

Conclusions: The endoscopic treatment for VUR with Deflux, is a good alternative to medical treatment especially in single ureter with low grade. Therefore the authors recommend this technique at the time of counseling parents.

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Dextrans / therapeutic use*
  • Female
  • Humans
  • Hyaluronic Acid / therapeutic use*
  • Male
  • Prostheses and Implants*
  • Ureteroscopy
  • Vesico-Ureteral Reflux / surgery*

Substances

  • Dextrans
  • deflux
  • Hyaluronic Acid