Diastereoselective spiroannulation of phenolic substrates: synthesis of (+/-)-2-tert-butyl-6-methoxy-1-oxaspiro[4,5]deca-6,9-diene-8-one

Molecules. 2005 Oct 31;10(10):1335-9. doi: 10.3390/10101335.

Abstract

The synthesis of a new spiroether is described. The title compound is obtained as a diastereomeric mixture in 45% yield.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cyclohexanones / chemical synthesis*
  • Furans / chemical synthesis*
  • Models, Biological
  • Molecular Conformation
  • Oxidation-Reduction
  • Phenols / chemistry*
  • Spiro Compounds / chemical synthesis*
  • Spiro Compounds / chemistry*

Substances

  • 2-tert-butyl-6-methoxy-1-oxaspiro(4,5)deca-6,9-diene-8-one
  • Cyclohexanones
  • Furans
  • Phenols
  • Spiro Compounds