Reactivity of 4-tert-butyldimethylsiloxy-1,2,3,6-tetrahydropyridines with hydrazines

Molecules. 2006 Nov 30;11(11):929-39. doi: 10.3390/11110929.

Abstract

The reactivity of 6-(nitrophenyl or trimethoxyphenyl)-4-tert-butyldimethyl- siloxy-1,2,3,6-tetrahydropyridine derivatives with hydrazines under acid conditions is described. The structure of the products isolated - hydrazones, pyrazolines or pyridazinones - depended on the conditions used. In addition, a systematic study of the reaction outcomes was carried out by introducing variations on the substituents of the tetrahydropyridine ring.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Carbon Isotopes
  • Hydrazines / chemistry*
  • Magnetic Resonance Spectroscopy
  • Protons
  • Pyridines / chemistry*
  • Siloxanes / chemistry*

Substances

  • Carbon Isotopes
  • Hydrazines
  • Protons
  • Pyridines
  • Siloxanes