A computational framework for the analysis of biological models

Annu Int Conf IEEE Eng Med Biol Soc. 2007:2007:1101-4. doi: 10.1109/IEMBS.2007.4352488.

Abstract

We present a computational framework for the visualization of large datasets produced from simulated multidimensional biological cell and tissue models. In this work we present a subsystem of a complete biological simulation system called BioPSiS (Biological Process Simulation System). The host system consists of special subsystems which monitor the simulation process and visualize its results. The mathematical computations in BioPSis can be performed either in a simple processing unit or in a distributed unit. The functionality of the subsystem presented here provides an interactive tool. In particular this intuitive visualization subsystem facilitates the analysis of the simulation results as well as the evaluation of the computational efficiency. Case studies and experiments demonstrate the efficacy of the proposed approach in terms of its ease to use, as well as its various features such as the capability to extract complex information from the output data for further study.

MeSH terms

  • Algorithms*
  • Computer Graphics*
  • Computer Simulation*
  • Imaging, Three-Dimensional / methods*
  • Models, Biological*
  • User-Computer Interface*