Kinetic theory is used to investigate cross-stream migration of a rigid polymer undergoing rectilinear flow in the vicinity of a wall. Hydrodynamic interactions between the polymers and the boundary result in a cross-stream migration. In simple shear flow, polymers migrate away from the wall, creating a depletion layer in the vicinity of the wall which thickens as the flow strength increases relative to the Brownian force. In pressure-driven flow, an off-center maximum in the center-of-mass distribution occurs due to a competition between hydrodynamic interactions with the wall and the anisotropic diffusivity induced by the inhomogeneous flow field.