Risk factors for acute retinopathy of prematurity

Ann Ophthalmol (Skokie). 2007 Spring;39(2):107-11. doi: 10.1007/s12009-007-0015-8.

Abstract

We prospectively studied the risk factors and the incidence of retinopathy of prematurity (ROP) in 195 consecutive preterm infants. Birth weight and duration of mechanical ventilation were the only factors significantly associated with the incidence of ROP. While indomethacin increases the risk of developing ROP, maternal antenatal steroids have a protective effect against the development of severe stages of ROP. The presence of intraventricular hemorrhage increases the risk of severe ROP.

MeSH terms

  • Birth Weight
  • Cerebral Hemorrhage / complications
  • Cerebral Hemorrhage / prevention & control
  • Female
  • Gestational Age
  • Humans
  • Incidence
  • Indomethacin / adverse effects
  • Indomethacin / therapeutic use
  • Infant, Newborn
  • Infant, Premature
  • Pregnancy / metabolism
  • Prospective Studies
  • Respiration, Artificial / adverse effects
  • Retinopathy of Prematurity / epidemiology
  • Retinopathy of Prematurity / etiology*
  • Retinopathy of Prematurity / physiopathology
  • Risk Factors
  • Severity of Illness Index
  • Steroids / metabolism
  • Time Factors

Substances

  • Steroids
  • Indomethacin