Motor Proteins: tightening your belt with myosin VI

Curr Biol. 2007 Nov 6;17(21):R915-7. doi: 10.1016/j.cub.2007.09.003.

Abstract

New work shows that the motor protein myosin VI, acting through vinculin, plays a key role in the maturation of cadherin-based adherens junctions in epithelial cells.

MeSH terms

  • Adherens Junctions / metabolism
  • Animals
  • Cadherins / metabolism
  • Cell Adhesion
  • Cells, Cultured
  • Drosophila
  • Epithelial Cells / cytology
  • Epithelial Cells / metabolism
  • Humans
  • Models, Biological
  • Myosin Heavy Chains / metabolism*
  • Vinculin / metabolism

Substances

  • Cadherins
  • myosin VI
  • Vinculin
  • Myosin Heavy Chains