Abstract
Mastocytosis is a disorder characterised by abnormal mast cell proliferation. The diverse spectrum of clinical presentations is dependent on the tissues and organs involved. We report a rare case of aggressive systemic mastocytosis presenting in utero with diffuse cutaneous involvement, and haematological abnormalities. There is little published evidence to guide treatment.
MeSH terms
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Antineoplastic Agents, Phytogenic / therapeutic use*
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Ascites / etiology
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Fatal Outcome
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Female
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Fetal Distress / etiology*
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Fetal Distress / pathology
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Hepatomegaly / etiology
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Humans
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Infant, Newborn
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Male
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Mast Cells / pathology*
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Mastocytosis, Systemic / complications
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Mastocytosis, Systemic / drug therapy*
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Mastocytosis, Systemic / pathology
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Pregnancy
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Prenatal Care
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Skin Diseases / etiology*
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Skin Diseases / pathology
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Splenomegaly / etiology
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Treatment Failure
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Vincristine / therapeutic use*
Substances
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Antineoplastic Agents, Phytogenic
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Vincristine