Nickel-catalyzed beta-boration of alpha,beta-unsaturated esters and amides with bis(pinacolato)diboron

Koji Hirano; Hideki Yorimitsu; Koichiro Oshima

doi:10.1021/ol702254g

Nickel-catalyzed beta-boration of alpha,beta-unsaturated esters and amides with bis(pinacolato)diboron

Org Lett. 2007 Nov 22;9(24):5031-3. doi: 10.1021/ol702254g. Epub 2007 Nov 1.

Authors

Koji Hirano¹, Hideki Yorimitsu, Koichiro Oshima

Affiliation

¹ Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Kyoto-daigaku Katsura, Nishikyo-ku, Kyoto 615-8510, Japan.

PMID: 17973483
DOI: 10.1021/ol702254g

Abstract

A nickel catalyst system for beta-boration of alpha,beta-unsaturated esters and amides with bis(pinacolato)diboron has been developed. The catalyst system enables the boration of di-, tri-, and tetrasubstituted substrates in good yields.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Amides / chemistry*
Boron Compounds / chemistry*
Boronic Acids / chemical synthesis*
Boronic Acids / chemistry
Butanones / chemistry*
Catalysis
Esters / chemistry*
Molecular Structure
Nickel / chemistry*
Organometallic Compounds / chemistry*
Stereoisomerism

Substances

Amides
Boron Compounds
Boronic Acids
Butanones
Esters
Organometallic Compounds
bis(pinacolato)diboron
Nickel