A novel triterpene from Centella asiatica

Quan-Lin Yu; Hong-Quan Duan; Yoshihisa Takaishi; Wen-Yuan Gao

doi:10.3390/11090661

A novel triterpene from Centella asiatica

Molecules. 2006 Sep 4;11(9):661-5. doi: 10.3390/11090661.

Authors

Quan-Lin Yu¹, Hong-Quan Duan, Yoshihisa Takaishi, Wen-Yuan Gao

Affiliation

¹ College of Pharmaceutical Sciences and Biotechnology, Tianjin University, Tianjin 300072, PR China. quanlin_yu@yahoo.com.cn

Abstract

A novel triterpene, 2alpha,3beta,20,23-tetrahydroxyurs-28-oic acid (1), was isolated from the aerial part of Centella asiatica. Its structure was elucidated by spectroscopic methods, including 2D-NMR spectra. It displayed no activity against Hela and A549 cell lines at concentrations of 10 and 30 microg/mL, respectively.

MeSH terms

Antineoplastic Agents, Phytogenic / chemistry
Antineoplastic Agents, Phytogenic / pharmacology
Centella / chemistry*
Female
HeLa Cells
Humans
Lung Neoplasms / drug therapy
Magnetic Resonance Spectroscopy
Triterpenes / chemistry*
Triterpenes / pharmacology
Uterine Cervical Neoplasms / drug therapy

Substances

Antineoplastic Agents, Phytogenic
Triterpenes