Ratio of high-, medium-, and low-molecular weight serum adiponectin to the total adiponectin value in children

Rimei Nishimura; Aya Morimoto; Toru Matsudaira; Yumi Miyashita; Hironari Sano; Takako Shirasawa; Eiko Takahashi; Naoko Tajima

doi:10.1016/j.jpeds.2007.07.047

Ratio of high-, medium-, and low-molecular weight serum adiponectin to the total adiponectin value in children

J Pediatr. 2007 Nov;151(5):545-7, 547.e1-2. doi: 10.1016/j.jpeds.2007.07.047.

Authors

Rimei Nishimura¹, Aya Morimoto, Toru Matsudaira, Yumi Miyashita, Hironari Sano, Takako Shirasawa, Eiko Takahashi, Naoko Tajima

Affiliation

¹ Division of Diabetes, Metabolism, and Endocrinology, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, Japan. rimei@jikei.ac.jp

PMID: 17961704
DOI: 10.1016/j.jpeds.2007.07.047

Abstract

In 760 children age 9 to 10 years, the serum adiponectin composition (high molecular weight [HMW], hexameric medium molecular weight [MMW], and trimeric low molecular weight [LMW]) was found to vary markedly depending on whether the total adiponectin value was high or low. A lower total adiponectin value was associated with a lower ratio of HMW adiponectin.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adiponectin / blood*
Body Mass Index
Child
Enzyme-Linked Immunosorbent Assay
Female
Humans
Japan
Male
Molecular Weight

Substances

Adiponectin