Abstract
Acamprosate, a drug used to treat alcohol dependence, was first reported as a potential treatment for tinnitus in 2005. The drug may improve tinnitus by a dual mechanism of action, acting both as a glutamate antagonist and as a GABA agonist. It is suggested that its action may be both on the ear and the nervous system.
MeSH terms
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Acamprosate
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Alcohol Deterrents / therapeutic use*
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Excitatory Amino Acid Antagonists
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GABA Agents / therapeutic use
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Humans
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Taurine / analogs & derivatives*
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Taurine / therapeutic use
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Tinnitus / drug therapy*
Substances
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Alcohol Deterrents
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Excitatory Amino Acid Antagonists
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GABA Agents
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Taurine
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Acamprosate