Quadruply hydrogen-bonded building block from hydrazide-quinolinone motif and gelation ability of its analogous oxalic monoester-monoamide derivative

Yong Yang; Hui-Juan Yan; Chuan-Feng Chen; Li-Jun Wan

doi:10.1021/ol702194z

Quadruply hydrogen-bonded building block from hydrazide-quinolinone motif and gelation ability of its analogous oxalic monoester-monoamide derivative

Org Lett. 2007 Nov 22;9(24):4991-4. doi: 10.1021/ol702194z. Epub 2007 Oct 23.

Authors

Yong Yang¹, Hui-Juan Yan, Chuan-Feng Chen, Li-Jun Wan

Affiliation

¹ Beijing National Laboratory for Molecular Sciences, Center for Chemical Biology, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, China.

PMID: 17956109
DOI: 10.1021/ol702194z

Abstract

NMR and STM studies revealed that the hydrazide-quinolinone-based building block 5 exhibited a monomer-dimer-polymer equilibrium, while its acyclic analogue 6, due to conformational flexibility, exhibited a more complicated mode of aggregation and formed a gel in dichloromethane/hexane.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Amides / chemical synthesis*
Amides / chemistry
Esters / chemical synthesis*
Esters / chemistry
Gels / chemical synthesis
Gels / chemistry
Hydrogen Bonding
Magnetic Resonance Spectroscopy / methods
Microscopy, Scanning Tunneling / methods
Molecular Structure
Particle Size
Quinolones / chemistry*

Substances

Amides
Esters
Gels
Quinolones