Waddlia chondrophila, a potential agent of human fetal death

Emerg Infect Dis. 2007 Aug;13(8):1239-43. doi: 10.3201/eid1308.070315.

Abstract

We investigated the zoonotic potential of Waddlia chon-drophila, a new Chlamydia-like abortigenic agent in ruminants. Anti-Waddlia antibody reactivity was tested by immunofluorescence and Western blot. Waddlia seroprevalence was higher in women who had had sporadic and recurrent miscarriages than in control women (p < 0.001). Waddlia spp. may represent a cause of human fetal loss.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Abortion, Habitual / microbiology
  • Abortion, Spontaneous / epidemiology
  • Abortion, Spontaneous / microbiology
  • Adult
  • Animals
  • Blotting, Western / methods
  • Chlamydiaceae Infections / epidemiology*
  • Chlamydiaceae Infections / microbiology
  • Chlamydiales / isolation & purification*
  • Female
  • Fetal Death / epidemiology
  • Fetal Death / microbiology*
  • Fluorescent Antibody Technique / methods
  • Humans
  • Immunoglobulin G / blood
  • Pregnancy
  • Pregnancy Complications, Infectious / epidemiology
  • Pregnancy Complications, Infectious / microbiology*
  • Seroepidemiologic Studies
  • Zoonoses / epidemiology
  • Zoonoses / microbiology

Substances

  • Immunoglobulin G