[Traceability of a resorbable implant for lipoatrophy: why should it be traced and how should this be done? Example of polylactic acid (Newfill)]

Med Mal Infect. 2007 Dec;37(12):824-7. doi: 10.1016/j.medmal.2007.09.006. Epub 2007 Oct 18.
[Article in French]

Abstract

Facial lipoatrophy is a frequent adverse effect of HIV-infected patients due to antiretroviral therapy. Intradermal injection of polylactic acid (Newfill) is one of the currently available treatments. Newfill is a resorbable implant and follow-up has to be rigorous. The Pharmacy and the Infectious Diseases units at the Saint-Louis hospital implemented a follow-up procedure. A follow-up of treated patients was made for 20 months. 127 patients were included. The rate of traceability was 100%. Such traceability is therefore feasible and will have to be implemented for the follow-up of patients treated with future filling products.

MeSH terms

  • Absorbable Implants*
  • Face
  • Female
  • HIV-Associated Lipodystrophy Syndrome / surgery*
  • Humans
  • Lactic Acid / analysis*
  • Male
  • Polyesters
  • Polymers / analysis*

Substances

  • Polyesters
  • Polymers
  • Lactic Acid
  • poly(lactide)