Fourth order approaches for localization of brain current sources

Conf Proc IEEE Eng Med Biol Soc. 2006:2006:4498-501. doi: 10.1109/IEMBS.2006.260063.

Abstract

Two high resolution methods solving inverse problems potentially ill-posed, named 4-MUSIC and 4-RapMUSIC, are proposed. They allow for localization of brain current sources with unconstrained orientations from surface electro-or magneto-encephalographic data using spherical or realistic head geometries. The 4-MUSIC and 4-RapMUSIC methods are based on i) the separability of the data transfer matrix as a function of location and orientation parameters and ii) the fourth order (FO) virtual array theory. In addition, 4-RapMUSIC uses the deflation concept extended to FO statistics accounting for the presence of potentially but not totally coherent sources. Computer results display the superiority of the 4-RapMUSIC approach in different situations (two closed sources, additive Gaussian noise with unknown spatial covariance, ...) especially over classical algorithms.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms
  • Brain / anatomy & histology*
  • Brain Mapping
  • Computer Simulation
  • Electrodes
  • Electroencephalography / instrumentation
  • Electroencephalography / methods
  • Equipment Design
  • Head
  • Humans
  • Magnetoencephalography / instrumentation
  • Magnetoencephalography / methods
  • Models, Neurological
  • Models, Statistical
  • Normal Distribution
  • Signal Processing, Computer-Assisted
  • Software