Model order selection for quantification of a multi-exponential magnetic resonance spectrum

Conf Proc IEEE Eng Med Biol Soc. 2006:2006:1299-302. doi: 10.1109/IEMBS.2006.260107.

Abstract

Magnetic resonance spectroscopic signals analyzed by time-domain models in order to retrieve estimates of the model parameters usually require prior knowledge about the model order. For multi-exponential signals where a superposition of peaks occurs at the same resonance frequency, but with different damping values, model order selection criteria from information theory can be used. In this study, several generalized versions of information criteria are compared using Monte-Carlo simulation signals. The best criterion is further applied for selecting the model order of experimental glycogen signals.

Publication types

  • Comparative Study
  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms*
  • Animals
  • Computer Simulation
  • Glucose / metabolism*
  • Glycogen / metabolism*
  • Liver / metabolism*
  • Magnetic Resonance Spectroscopy / methods*
  • Metabolic Clearance Rate
  • Models, Biological*
  • Rats
  • Reproducibility of Results
  • Sensitivity and Specificity

Substances

  • Glycogen
  • Glucose