Copper-catalyzed alkene aziridination with N-tosyloxycarbamates

Org Lett. 2007 Nov 8;9(23):4797-800. doi: 10.1021/ol702152e. Epub 2007 Oct 18.

Abstract

Pyridine copper complexes were found as active catalysts for the intramolecular aziridination of allylic N-tosyloxycarbamates and the intermolecular aziridination of styrenes with trichloroethyl N-tosyloxycarbamates. Free aziridines were easily obtained by basic deprotection of the trichloroethyl group.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alkenes / chemical synthesis*
  • Alkenes / chemistry
  • Aziridines / chemistry*
  • Carbamates / chemistry*
  • Catalysis
  • Copper
  • Molecular Structure
  • Oxygen / chemistry*
  • Styrenes / chemistry

Substances

  • Alkenes
  • Aziridines
  • Carbamates
  • Styrenes
  • Copper
  • Oxygen