Violacein: properties and biological activities

Biotechnol Appl Biochem. 2007 Nov;48(Pt 3):127-33. doi: 10.1042/BA20070115.

Abstract

The violet pigment violacein is an indole derivative, isolated mainly from bacteria of the genus Chromobacterium, which exhibits important antitumoral, antimicrobial and antiparasitary properties. Furthermore, the formulation of violacein in different polymeric carriers developed so far offers alternative approaches to overcoming physiological barriers and undesirable physicochemical properties in vivo, thus improving its efficacy.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Anti-Infective Agents / adverse effects
  • Anti-Infective Agents / chemistry*
  • Anti-Infective Agents / pharmacology*
  • Antineoplastic Agents / adverse effects
  • Antineoplastic Agents / chemistry*
  • Antineoplastic Agents / pharmacology*
  • Chromobacterium / chemistry
  • Humans
  • Indoles / adverse effects
  • Indoles / chemistry*
  • Indoles / pharmacology*

Substances

  • Anti-Infective Agents
  • Antineoplastic Agents
  • Indoles
  • violacein