Combined voriconazole plus caspofungin therapy for the treatment of probable Geotrichum pneumonia in a leukemia patient

Infection. 2008 Feb;36(1):65-7. doi: 10.1007/s15010-007-6235-4. Epub 2007 Oct 9.

Abstract

Infections by Geotrichum capitatum, occurring in leukemia patients, are rarely reported and generally are characterized by a poor prognosis. Here we reported a case of G. capitatum pneumonia in a patient with plasma cell leukemia, successfully treated with antifungal combination with voriconazole and caspofungin and supportive therapy.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Antifungal Agents / administration & dosage*
  • Antifungal Agents / pharmacology
  • Antifungal Agents / therapeutic use
  • Caspofungin
  • Drug Therapy, Combination
  • Echinocandins / administration & dosage*
  • Echinocandins / pharmacology
  • Echinocandins / therapeutic use
  • Female
  • Geotrichosis / drug therapy*
  • Geotrichosis / microbiology
  • Geotrichum
  • Humans
  • Immunocompromised Host
  • Leukemia, Plasma Cell / complications
  • Leukemia, Plasma Cell / drug therapy
  • Lipopeptides
  • Lung Diseases, Fungal / complications
  • Lung Diseases, Fungal / drug therapy*
  • Lung Diseases, Fungal / microbiology
  • Pyrimidines / administration & dosage*
  • Pyrimidines / pharmacology
  • Pyrimidines / therapeutic use
  • Triazoles / administration & dosage*
  • Triazoles / pharmacology
  • Triazoles / therapeutic use
  • Voriconazole

Substances

  • Antifungal Agents
  • Echinocandins
  • Lipopeptides
  • Pyrimidines
  • Triazoles
  • Caspofungin
  • Voriconazole