Variation in the FTO gene locus is associated with cerebrocortical insulin resistance in humans

Diabetologia. 2007 Dec;50(12):2602-3. doi: 10.1007/s00125-007-0839-1. Epub 2007 Oct 5.
No abstract available

Publication types

  • Comparative Study
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alpha-Ketoglutarate-Dependent Dioxygenase FTO
  • Body Mass Index
  • Cerebral Cortex / metabolism*
  • Cerebral Cortex / pathology
  • Female
  • Genetic Predisposition to Disease
  • Genotype
  • Humans
  • Insulin / metabolism
  • Insulin / pharmacology
  • Insulin Resistance / genetics*
  • Insulin-Secreting Cells / drug effects
  • Insulin-Secreting Cells / metabolism
  • Linkage Disequilibrium
  • Male
  • Obesity / genetics
  • Obesity / metabolism
  • Overweight / genetics
  • Overweight / metabolism
  • Polymorphism, Genetic*
  • Proteins / genetics*

Substances

  • Insulin
  • Proteins
  • Alpha-Ketoglutarate-Dependent Dioxygenase FTO
  • FTO protein, human