Urinary excretion of zinc and metabolic control of patients with diabetes type 2

Biol Trace Elem Res. 2007 Winter;120(1-3):42-50. doi: 10.1007/s12011-007-8000-z.

Abstract

The objective of this study was to assess urinary excretion of zinc and evaluation parameters of metabolic control in type 2 diabetic patients. Thirty-one type 2 diabetic patients, of both genders, with 5.8 +/- 5.6 years average time of the disease, age range 20-60 years, were selected. Evaluation of the nutritional status was performed using anthropometric measurements. To evaluate food consumption, the 3-day alimentary log method was used, and its analysis was performed using a software. Determination of urinary zinc was by atomic absorption spectrophotometry. From the obtained results, it was concluded that 51.6% of the patients were overweight. The mean of found waist circumference was 100.4 and 92.2 cm for men and women, respectively. Blood glucose and glycated hemoglobin values were higher than reference values, and plasma albumin concentration was adequate. The median of found urinary zinc excretion was 474.9 mug/24 h, within normal standards (300-600 mug/day). Regarding diet composition, calorie and protein concentration were above recommendation, while mean zinc concentration was adequate. This data allow the conclusion that the evaluated patients presented adequate urinary zinc excretion in comparison with reference values.

MeSH terms

  • Adult
  • Diabetes Mellitus, Type 2 / urine*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Zinc / urine*

Substances

  • Zinc