Synthesis and biological activity of furostanic analogues of brassinosteroids bearing the 5alpha-hydroxy-6-oxo moiety

Margarita Romero-Avila; Guadalupe de Dios-Bravo; Jóse M Mendez-Stivalet; Rogelio Rodríguez-Sotres; Martin A Iglesias-Arteaga

doi:10.1016/j.steroids.2007.08.007

Synthesis and biological activity of furostanic analogues of brassinosteroids bearing the 5alpha-hydroxy-6-oxo moiety

Steroids. 2007 Dec;72(14):955-9. doi: 10.1016/j.steroids.2007.08.007. Epub 2007 Aug 23.

Authors

Margarita Romero-Avila¹, Guadalupe de Dios-Bravo, Jóse M Mendez-Stivalet, Rogelio Rodríguez-Sotres, Martin A Iglesias-Arteaga

Affiliation

¹ Facultad de Química, Universidad Nacional Autónoma de México, Ciudad Universitaria, 04510, México, DF, Mexico.

PMID: 17905389
DOI: 10.1016/j.steroids.2007.08.007

Abstract

Two furostanic analogues of brassinosteroids bearing the 5alpha-hydroxy-6-oxo moiety were synthesized and their biological activity studied using the bean second internode elongation test. One of the compounds produced significant stimulation at doses of 2.5 and 5ng/plant.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Cholestanones / pharmacology
Dose-Response Relationship, Drug
Molecular Structure
Phaseolus / drug effects
Phaseolus / growth & development
Plant Growth Regulators / chemical synthesis
Plant Growth Regulators / chemistry*
Plant Growth Regulators / pharmacology*
Seeds / drug effects
Seeds / growth & development
Steroids, Heterocyclic / chemical synthesis*
Steroids, Heterocyclic / chemistry
Steroids, Heterocyclic / pharmacology*

Substances

Cholestanones
Plant Growth Regulators
Steroids, Heterocyclic
homobrassinolide