[A case of vasculitis in chronic hepatitis C patient treated with pegylated interferon alpha-2a and ribavirin]

Korean J Hepatol. 2007 Sep;13(3):419-22. doi: 10.3350/kjhep.2007.13.3.419.
[Article in Korean]

Abstract

There has been an increase in the number of patients treated with pegylated interferon (PEG-IFN) and ribavirin due to the better antiviral efficacy. The main serious adverse events of PEG-IFN plus ribavirin combination therapy are bone marrow suppression and hemolytic anemia. However, there are few reports of vasculitis occurring during PEG-IFN therapy. We describe a patient who developed vasculitis during the treatment of chronic hepatitis C with PEG-IFN and ribavirin.

Publication types

  • Case Reports

MeSH terms

  • Antiviral Agents / adverse effects*
  • Drug Therapy, Combination
  • Female
  • Hepatitis C, Chronic / drug therapy*
  • Humans
  • Interferon alpha-2
  • Interferon-alpha / adverse effects*
  • Liver Function Tests
  • Middle Aged
  • Polyethylene Glycols / adverse effects*
  • Recombinant Proteins
  • Ribavirin / adverse effects*
  • Skin / drug effects
  • Vasculitis / chemically induced*

Substances

  • Antiviral Agents
  • Interferon alpha-2
  • Interferon-alpha
  • Recombinant Proteins
  • Polyethylene Glycols
  • Ribavirin
  • peginterferon alfa-2a