TandTRAQ: an open-source tool for integrated protein identification and quantitation

Bioinformatics. 2007 Dec 15;23(24):3394-6. doi: 10.1093/bioinformatics/btm467. Epub 2007 Sep 25.

Abstract

Integrating qualitative protein identification with quantitative protein analysis is non-trivial, given incompatibility in output formats. We present TandTRAQ, a standalone utility that integrates results from i-Tracker, an open-source iTRAQ quantitation program with the search results from X?Tandem, an open-source proteome search engine. The utility runs from the command-line and can be easily integrated into a pipeline for automation.

Availability: The TandTRAQ Perl scripts are freely available for download at http://www.ohsucancer.com/isrdev/tandtraq/

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Algorithms
  • Database Management Systems*
  • Databases, Protein*
  • Information Storage and Retrieval / methods*
  • Programming Languages
  • Proteins / chemistry*
  • Sequence Alignment / methods
  • Sequence Analysis, Protein / methods*
  • Software*
  • Systems Integration

Substances

  • Proteins