Effects of isometric handgrip training among people medicated for hypertension: a multilevel analysis

Blood Press Monit. 2007 Oct;12(5):307-14. doi: 10.1097/MBP.0b013e3282cb05db.

Abstract

Objective: To examine the longitudinal effects of isometric handgrip (IHG) exercise training on blood pressure using hierarchical linear modeling.

Methods: Data from 43 participants who were medicated for hypertension at the time of training were amalgamated from three previous investigations. In each study, IHG training was completed 3 days/week for 8 weeks at 30% of maximal voluntary contraction and resting blood pressure was assessed at twice-weekly intervals throughout.

Results: Hierarchical linear modeling analysis revealed a linear pattern of blood pressure decline over time with estimated reductions of 5.7 and 3 mmHg reductions in systolic and diastolic pressure, respectively. Participants with higher initial systolic pressure showed greater rates of blood pressure decline (r=-0.67), inferring that individuals with higher blood pressure stand to achieve greater benefits from this method of training.

Conclusions: These results provide further evidence that IHG training lowers resting blood pressure among persons medicated for hypertension.

MeSH terms

  • Adult
  • Aged
  • Angiotensin-Converting Enzyme Inhibitors / therapeutic use
  • Blood Pressure / drug effects
  • Blood Pressure / physiology*
  • Calcium Channel Blockers / therapeutic use
  • Diuretics / therapeutic use
  • Exercise / physiology
  • Exercise Therapy*
  • Female
  • Hand Strength / physiology
  • Humans
  • Hypertension / drug therapy*
  • Hypertension / physiopathology*
  • Linear Models
  • Male
  • Middle Aged
  • Retrospective Studies

Substances

  • Angiotensin-Converting Enzyme Inhibitors
  • Calcium Channel Blockers
  • Diuretics