Inherited platelet disorders

Clin Chim Acta. 2008 Jan;387(1-2):1-8. doi: 10.1016/j.cca.2007.08.010. Epub 2007 Aug 31.

Abstract

Inherited platelet disorders are a rare, but probably underdiagnosed, cause of symptomatic bleeding. They are characterized by abnormalities of platelet number (inherited thrombocytopenias), function (inherited disorders of platelet function) or both. This review briefly discusses the inherited platelet disorders with respect to molecular defects, diagnostic evaluation and treatment strategies.

Publication types

  • Review

MeSH terms

  • Blood Platelets / cytology
  • Blood Platelets / physiology*
  • Hematologic Diseases / blood
  • Hematologic Diseases / classification
  • Hematologic Diseases / genetics*
  • Humans