Objective: To report 7 cases of acquired hemoglobin H in myelodysplastic syndromes.
Case data and discussion: Clinical materials of the 7 cases were retrospectively presented. Clinical features of the similar cases in literatures were reviewed. The criteria for diagnosis of this entity by Steensma and its pathogenesis were discussed.
Conclusion: This entity is a new subtype of MDS with unique clinical features and pathogenesis, and might be a proper model in the study of MDS transformation.