Abstract
From the fungus Stereum hirsutum have been isolated and identified two new epidioxysterols 1, 4, together with two known ones 2 and 3. Their structures were elucidated on the basis of spectroscopic analysis and chemical reactions. Epidioxysterols 1-4 have been shown to possess a significant activity against Mycobacterium tuberculosis.
MeSH terms
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Antitubercular Agents / chemistry
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Antitubercular Agents / isolation & purification
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Antitubercular Agents / pharmacology
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Basidiomycota / chemistry*
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Cholesterol Esters / chemistry
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Cholesterol Esters / isolation & purification
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Cholesterol Esters / pharmacology*
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Microbial Sensitivity Tests
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Molecular Structure
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Mycobacterium tuberculosis / drug effects*
Substances
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Antitubercular Agents
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Cholesterol Esters
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epidioxysterol