In situ generation of oxo-sulfidobis(dithiolene)tungsten(VI) complexes: active-site models for the aldehyde ferredoxin oxidoreductase family of tungsten enzymes

Hideki Sugimoto; Hiroyuki Tano; Reiko Tajima; Hiroyuki Miyake; Hiroshi Tsukube; Hiromi Ohi; Shinobu Itoh

doi:10.1021/ic7012733

In situ generation of oxo-sulfidobis(dithiolene)tungsten(VI) complexes: active-site models for the aldehyde ferredoxin oxidoreductase family of tungsten enzymes

Inorg Chem. 2007 Oct 15;46(21):8460-2. doi: 10.1021/ic7012733. Epub 2007 Sep 14.

Authors

Hideki Sugimoto¹, Hiroyuki Tano, Reiko Tajima, Hiroyuki Miyake, Hiroshi Tsukube, Hiromi Ohi, Shinobu Itoh

Affiliation

¹ Department of Chemistry, Graduate School of Science, Osaka City University, Osaka 558-8585, Japan. sugimoto@sci.osaka-cu.ac.jp

PMID: 17854180
DOI: 10.1021/ic7012733

Abstract

Oxo-sulfidobis(dithiolene)tungsten(VI) complexes were prepared in situ by the reaction of oxobis(dithiolene)tungsten(V) precursors with hydrosulfide (SH-). The complexes, characterized by UV-vis, electrospray ionization mass spectrometry, IR, and resonance Raman spectroscopies, model the proposed coordination environment and observed hydrolytic reactions of members of the aldehyde ferredoxin oxidoreductase family of tungsten enzymes.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Binding Sites
Chemistry, Inorganic / methods*
Kinetics
Ligands
Models, Chemical
Molecular Conformation
Molecular Structure
Pyruvate Synthase / chemistry*
Spectrometry, Mass, Electrospray Ionization / methods
Spectrophotometry, Infrared / methods
Spectrum Analysis, Raman / methods
Substrate Specificity
Tungsten / analysis*

Substances

Ligands
Pyruvate Synthase
Tungsten