Calcium phosphate-based coatings on titanium and its alloys

J Biomed Mater Res B Appl Biomater. 2008 Apr;85(1):279-99. doi: 10.1002/jbm.b.30932.

Abstract

Use of titanium as biomaterial is possible because of its very favorable biocompatibility with living tissue. Titanium implants having calcium phosphate coatings on their surface show good fixation to the bone. This review covers briefly the requirements of typical biomaterials and narrowly focuses on the works on titanium. Calcium phosphate ceramics for use in implants are introduced and various methods of producing calcium phosphate coating on titanium substrates are elaborated. Advantages and disadvantages of each type of coating from the view point of process simplicity, cost-effectiveness, stability of the coatings, coating integration with the bone, cell behavior, and so forth are highlighted. Taking into account all these factors, the efficient method(s) of producing these coatings are indicated finally.

Publication types

  • Review

MeSH terms

  • Alloys / chemistry*
  • Body Fluids / chemistry
  • Calcium Phosphates / chemistry*
  • Ceramics / chemistry
  • Coated Materials, Biocompatible / chemistry
  • Corrosion
  • Humans
  • Prostheses and Implants
  • Surface Properties
  • Titanium / chemistry*

Substances

  • Alloys
  • Calcium Phosphates
  • Coated Materials, Biocompatible
  • calcium phosphate
  • Titanium