Multifunctionalised cationic fullerene adducts for gene transfer: design, synthesis and DNA complexation

Chem Commun (Camb). 2007 Sep 28:(36):3762-4. doi: 10.1039/b708435h. Epub 2007 Jul 5.

Abstract

Cationic poly-N,N-dimethylfulleropyrrolidinium derivatives have been designed and synthesised to complex plasmid DNA for gene delivery.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • DNA / pharmacology*
  • DNA / ultrastructure
  • Electrophoresis
  • Fullerenes / chemistry*
  • Fullerenes / pharmacology
  • Gene Transfer Techniques*
  • Molecular Structure
  • Plasmids / chemistry

Substances

  • Fullerenes
  • DNA