Synthesis of tamiflu and its phosphonate congeners possessing potent anti-influenza activity

MeSH terms

• Animals
• Antiviral Agents / chemical synthesis*
• Antiviral Agents / chemistry
• Antiviral Agents / pharmacology
• Cell Line
• Dogs
• Enzyme Inhibitors / chemical synthesis
• Enzyme Inhibitors / chemistry
• Enzyme Inhibitors / pharmacology
• Influenza A Virus, H1N1 Subtype / drug effects*
• Influenza A Virus, H1N1 Subtype / enzymology
• Influenza A Virus, H5N1 Subtype / drug effects*
• Influenza A Virus, H5N1 Subtype / enzymology
• Kinetics
• Models, Molecular
• Neuraminidase / antagonists & inhibitors
• Organophosphonates / chemical synthesis
• Organophosphonates / chemistry
• Organophosphonates / pharmacology
• Oseltamivir / analogs & derivatives*
• Oseltamivir / chemical synthesis*
• Oseltamivir / chemistry
• Oseltamivir / pharmacology