Abstract
A new geranylated isoflavone, 7-O-geranyl-6-methoxypseudobaptigenin (1) was isolated from the stem barks of Millettia conraui, along with known compounds 5-methoxydurmillone (2), conrauinone A (3), beta-amyrine (4), sitosterol (5), 3-O-beta-D-glucopyranosyl sitosterol (6) and n-docosanol (7). Compounds 1 and 4 showed a significant alpha-glucosidase inhibitory activity. The structures of the compounds were determined by analysis of their spectroscopic data.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
1-Deoxynojirimycin / pharmacology
-
Enzyme Inhibitors / isolation & purification*
-
Enzyme Inhibitors / pharmacology*
-
Glycoside Hydrolase Inhibitors*
-
Magnetic Resonance Spectroscopy
-
Millettia / chemistry*
-
Plant Bark / chemistry
-
Plant Stems / chemistry
-
Spectrometry, Mass, Electrospray Ionization
-
Spectrophotometry, Infrared
-
Spectrophotometry, Ultraviolet
Substances
-
Enzyme Inhibitors
-
Glycoside Hydrolase Inhibitors
-
1-Deoxynojirimycin