Metabolites from the xylariaceous fungus PSU-A80

Chem Pharm Bull (Tokyo). 2007 Sep;55(9):1316-8. doi: 10.1248/cpb.55.1316.

Abstract

One hypoxylonol, xylarenol (1), one hexadienoic acid, xylarenoic acid (2), and one tetralone, xylarenone (3), were isolated from the xylariaceous fungus PSU-A80 together with ten known compounds. The structures were established by analysis of spectroscopic data. 8-Methoxy-1-naphthol, one of the known metabolites, displayed good radical scavenging potency with an IC(50) value of 30 microg/ml.

MeSH terms

  • Antioxidants / chemistry*
  • Antioxidants / isolation & purification
  • Ascomycota / chemistry*
  • Ascomycota / metabolism*
  • Biphenyl Compounds
  • Culture Media
  • Fermentation
  • Free Radical Scavengers / chemistry
  • Free Radical Scavengers / isolation & purification
  • Magnetic Resonance Spectroscopy
  • Molecular Sequence Data
  • Picrates / chemistry
  • Spectrometry, Mass, Electrospray Ionization
  • Spectrophotometry, Infrared
  • Spectrophotometry, Ultraviolet

Substances

  • Antioxidants
  • Biphenyl Compounds
  • Culture Media
  • Free Radical Scavengers
  • Picrates
  • 1,1-diphenyl-2-picrylhydrazyl