Nonparaxial vector-field modeling of optical coherence tomography and interferometric synthetic aperture microscopy

J Opt Soc Am A Opt Image Sci Vis. 2007 Sep;24(9):2527-42. doi: 10.1364/josaa.24.002527.

Abstract

A large-aperture, electromagnetic model for coherent microscopy is presented and the inverse scattering problem is solved. Approximations to the model are developed for near-focus and far-from-focus operations. These approximations result in an image-reconstruction algorithm consistent with interferometric synthetic aperture microscopy (ISAM): this validates ISAM processing of optical-coherence-tomography and optical-coherence-microscopy data in a vectorial setting. Numerical simulations confirm that diffraction-limited resolution can be achieved outside the focal plane and that depth of focus is limited only by measurement noise and/or detector dynamic range. Furthermore, the model presented is suitable for the quantitative study of polarimetric coherent microscopy systems operating within the first Born approximation.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Algorithms
  • Computer Simulation
  • Electromagnetic Phenomena*
  • Image Processing, Computer-Assisted
  • Microscopy, Interference*
  • Models, Theoretical*
  • Reproducibility of Results
  • Tomography, Optical Coherence*