Use of sclerosing agent in the management of oral and perioral hemangiomas: review and case reports

Med Sci Monit. 2007 Sep;13(9):CS114-119.

Abstract

Background: Most cutaneous hemangiomas involute spontaneously. However, the lesion existing on the face poses a cosmetic problem while waiting for involution.

Case reports: Three hemangioma cases were treated by repeated local injection of 5% ethanolamine oleate solution. The lesions flattened and markedly reduced in size as shown by clinical and imaging evaluation.

Conclusions: Use of 5% ethanolamine oleate as a sclerosing agent for repeated intralesional injection in the management of facial hemangiomas is a safe treatment with acceptable results. As presented here, this technique offers the patient considerable relief of symptoms with minimal complications. However, the possibility of second-stage surgery to correct residual deformity is still considered. Sclerotherapy with ethanolamine oleate provides a good preparation for further surgery.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adolescent
  • Biomarkers, Tumor / metabolism
  • Female
  • Hemangioma / blood supply
  • Hemangioma / drug therapy*
  • Hemangioma / metabolism
  • Hemangioma / pathology*
  • Humans
  • Immunohistochemistry
  • Infant
  • Mouth Neoplasms / blood supply
  • Mouth Neoplasms / drug therapy*
  • Mouth Neoplasms / metabolism
  • Mouth Neoplasms / pathology*
  • Sclerosing Solutions / therapeutic use*
  • Sclerotherapy*
  • Tomography Scanners, X-Ray Computed

Substances

  • Biomarkers, Tumor
  • Sclerosing Solutions