Rational design of "turn-on" allosteric DNAzyme catalytic beacons for aqueous mercury ions with ultrahigh sensitivity and selectivity

Angew Chem Int Ed Engl. 2007;46(40):7587-90. doi: 10.1002/anie.200702006.

Authors

Juewen Liu¹, Yi Lu

Affiliation

¹ Department of Chemistry, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.

PMID: 17722216
DOI: 10.1002/anie.200702006

No abstract available

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Allosteric Regulation / drug effects
Base Sequence
Catalysis
Cations, Divalent
DNA, Catalytic / chemistry*
DNA, Catalytic / metabolism*
Drug Design
Mercury / analysis*
Mercury / pharmacology*
Molecular Sequence Data
Nucleic Acid Conformation
Sensitivity and Specificity

Substances

Cations, Divalent
DNA, Catalytic
Mercury