[From cocaine to innovative antiemetics. The medicinal chemistry of 5-ht3 receptor antagonists]

Pharm Unserer Zeit. 2007;36(5):354-61. doi: 10.1002/pauz.200700231.

[Article in German]

Authors

Heiko Zettl¹, Manfred Schubert-Zsilavecz, Carsten D Siebert

Affiliation

¹ Institut für Pharmazeutische Chemie, Zentrum für Arzneimittelforschung, Entwicklung und Sicherheit, Max-von-Laue-Str. 9, 60438 Frankfurt.

PMID: 17722162
DOI: 10.1002/pauz.200700231

No abstract available

Publication types

Review

MeSH terms

Animals
Antiemetics / chemistry
Antiemetics / pharmacokinetics
Antiemetics / pharmacology
Antiemetics / therapeutic use*
Antineoplastic Agents / adverse effects
Cocaine / chemistry
Cocaine / pharmacokinetics
Cocaine / pharmacology
Cocaine / therapeutic use*
Humans
Serotonin 5-HT3 Receptor Antagonists*
Serotonin Antagonists / chemistry
Serotonin Antagonists / pharmacokinetics
Serotonin Antagonists / pharmacology
Serotonin Antagonists / therapeutic use*
Structure-Activity Relationship
Vomiting / chemically induced
Vomiting / prevention & control*

Substances

Antiemetics
Antineoplastic Agents
Serotonin 5-HT3 Receptor Antagonists
Serotonin Antagonists
Cocaine