[Experience with only preoperative radiotherapy of non-metastatic rectal tumours]

Orv Hetil. 2007 Sep 2;148(35):1635-41. doi: 10.1556/OH.2007.28045.
[Article in Hungarian]

Abstract

Introduction: It is an accepted fact that the local recurrence rate can be decreased up to 50% for the metastatic rectum tumours irradiated only preoperatively.

Materials and methods: 181 patients having rectum tumour were irradiated preoperatively with 36 or 40 Gy between 1990 and 2001. The classification was made according to the modified Astler-Coller pathological staging system. The radiation treatment was carried out with telecobalt unit or high energy photon of linear accelerator after computerized radiation treatment planning.

Results: The most important characterizing factor for the efficiency of the preoperative irradiation is the local recurrence rate that was found to be 21.56% in our investigation. The survival rate was significantly influenced by the age of the patient and the applied dose.

Conclusion: Our statistical analysis was applied to investigate the efficiency of the only preoperatively irradiated patients. The results are in agreement with the reported contributions.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Digestive System Surgical Procedures / methods
  • Disease-Free Survival
  • Female
  • Humans
  • Hungary / epidemiology
  • Male
  • Middle Aged
  • Neoadjuvant Therapy / methods*
  • Neoplasm Recurrence, Local / epidemiology
  • Neoplasm Staging
  • Particle Accelerators
  • Radiotherapy Dosage
  • Radiotherapy Planning, Computer-Assisted
  • Radiotherapy, Adjuvant
  • Rectal Neoplasms / pathology
  • Rectal Neoplasms / radiotherapy*
  • Rectal Neoplasms / surgery*
  • Retrospective Studies
  • Survival Analysis
  • Treatment Outcome