Abstract
Acute mastoiditis, an infectious inflammatory process in the temporal bone, is an uncommon complication of otitis media. Here we describe a fatal case of mastoiditis complicated by thrombosis of the sigmoid sinus and intracerebral abscess caused by an unusual pathogen (Nocardia asteroides) in a person with HIV infection. Sulfonamides have remained the first-line agents for the management of Nocardia infections, but mortality remains high in patients with intracerebral infection.
MeSH terms
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AIDS-Related Opportunistic Infections / drug therapy
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AIDS-Related Opportunistic Infections / microbiology*
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AIDS-Related Opportunistic Infections / pathology
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Adult
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Brain Abscess / microbiology*
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Cranial Sinuses / pathology
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Fatal Outcome
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HIV Infections / complications*
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HIV Infections / drug therapy
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HIV Infections / microbiology
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HIV Infections / pathology
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Head / diagnostic imaging
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Humans
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Male
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Mastoiditis / complications*
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Mastoiditis / microbiology
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Mastoiditis / pathology
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Nocardia asteroides / isolation & purification
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Radiography
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Sinus Thrombosis, Intracranial