Protein-nanoparticle labelling probed by surface enhanced resonance Raman spectroscopy

Phil Douglas; Karen M McCarney; Duncan Graham; W Ewen Smith

doi:10.1039/b707660f

Protein-nanoparticle labelling probed by surface enhanced resonance Raman spectroscopy

Analyst. 2007 Sep;132(9):865-7. doi: 10.1039/b707660f. Epub 2007 Jul 31.

Authors

Phil Douglas¹, Karen M McCarney, Duncan Graham, W Ewen Smith

Affiliation

¹ Department of Pure & Applied Chemistry, University of Strathclyde, 295 Cathedral Street, Glasgow, UKG1 1XL.

PMID: 17710260
DOI: 10.1039/b707660f

Abstract

A benzotriazole dye has been attached to a heme protein via a Michael addition and the unique potential of surface enhanced resonance Raman scattering (SERRS) to provide informative in situ recognition of more than one label on one protein demonstrated.

MeSH terms

Animals
Coloring Agents
Cytochromes c / analysis
Maleimides
Nanoparticles*
Proteins / analysis*
Silver
Spectrum Analysis, Raman / methods*
Surface Properties
Triazoles

Substances

Coloring Agents
Maleimides
Proteins
Triazoles
Silver
benzotriazole
Cytochromes c