Abstract
We provide experimental and modeling evidence that the hydrodynamic environment can impact quorum sensing (QS) in a Pseudomonas aeruginosa biofilm. The amount of biofilm biomass required for full QS induction of the population increased as the flow rate increased.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Bacterial Proteins / genetics
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Bacterial Proteins / metabolism
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Biofilms / growth & development*
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Gene Expression Regulation, Bacterial
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Metalloendopeptidases / genetics
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Metalloendopeptidases / metabolism
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Models, Biological
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Pseudomonas aeruginosa / physiology*
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Quorum Sensing / physiology*
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Signal Transduction / physiology*
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Water / metabolism*
Substances
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Bacterial Proteins
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Water
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Metalloendopeptidases
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pseudolysin, Pseudomonas aeruginosa