Pseudoachalasia of the cardia secondary to nongastrointestinal neoplasia

Dysphagia. 2008 Jun;23(2):122-6. doi: 10.1007/s00455-007-9104-5. Epub 2007 Aug 15.

Abstract

A minor proportion of patients with achalasia eventually have a neoplasm and, as a consequence, pseudoachalasia is diagnosed. A neoplasm may either involve gastrointestinal junction or present a paraneoplastic effect. Over the global diagnoses of achalasia issued in 5 years of experience in our motility unit, we have found 13% (3/23 cases) of pseudoachalasia (2-4% in previous series, probably due to the fact that the population assisted was mainly composed of elderly patients). The origin of the neoplasm was bladder, prostate and metastases from epidermoid carcinoma of vocal chord. Treatment of primary neoplasm, besides classical approach (with dilatation of botulinum injection) may help in the resolution of this clinical disorder.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma / complications*
  • Aged
  • Aged, 80 and over
  • Botulinum Toxins, Type A / therapeutic use*
  • Colonic Neoplasms / complications*
  • Deglutition Disorders / diagnosis*
  • Deglutition Disorders / etiology*
  • Diagnosis, Differential
  • Esophageal Achalasia* / drug therapy
  • Esophageal Achalasia* / etiology
  • Esophageal Achalasia* / physiopathology
  • Humans
  • Male
  • Neuromuscular Agents / therapeutic use*
  • Paraneoplastic Syndromes
  • Urologic Neoplasms / complications*

Substances

  • Neuromuscular Agents
  • Botulinum Toxins, Type A